Tuesday, January 31, 2023

How Does Clindamycin Work For Acne

Possible Side Effects Of Clindamycin

Clindamycin gel for acne: Q& A with a dermatologist| Dr Dray
  • Skin problem: It causes dryness, burning, itching, and peeling of skin , erythema or redness , oiliness , new pimples or blemishes.
  • Infection: 10% of the consumers have exhibited fungal infection in cases of vaginal application.
  • Pseudomembranous colitis: Commonly known as an inflammation of the colon, though occurs with the use of other antibiotics as well, is a lethal condition commonly associated with clindamycin.
  • Adverse drug reaction: It includes diarrhea, nausea, vomiting, abdominal pain, cramps rashes, headache, watery or bloody stool. Diarrhea, bloody diarrhea and inflammation of the colon have been widely reported to the Food and Drug Administration, USA.

Who Should Not Use Tretinoin

Do not use tretinoin if:

  • You are allergic to tretinoin.
  • You are pregnant or breastfeeding, you are trying to get pregnant, or you are unsure whether you are pregnant. When prescribed as an oral medication, tretinoin was associated with miscarriage and birth defects. While there is inconclusive evidence that tretinoin applied topically can cause miscarriage or birth defects, it is best to be cautious. Tretinoin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

How To Use Clindamycin Topical For Acne:

Topical Clindamycin should be used over the entire affected area, so do not attempt to apply to only the pimples and âspot treatâ.

Applying over the entire face instead of spot treating will help prevent the occurrence of new pimples.

Clindamycin can be applied once or twice daily depending on your therapy.

For best results, apply at around the same time each day.

If you are applying twice daily, be sure to space out treatments by about 12 hours.

Apply to clean dry skin, and wash hands after application.

Avoid getting the product into eyes, mouth, or open wounds.

Wash the area thoroughly with water if contact occurs.

During treatment, do not wash your face more than 2-3 times daily to avoid skin drying out and causing worsening of acne.

Use gentle cleansers and face products during treatment.

If you are using cosmetics during your treatment, find products that are water-based or non-comedogenic .

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How Does Clindamycin Work To Fight Acne

Clindamycin works to treat acne by reducing the number of harmful bacteria that cause mild to moderate breakouts.

Using clindamycin for acne can also ease the pain and inflammation of infected acne caused by P. acnes.

Topical clindamycin is both bacteriostatic and bactericidal. This means that it works two ways: it stops bacteria from multiplying and kills these harmful cells directly.

It also prevents bacteria and sebum from clogging your pores and shuts down protein production.

Proteins are one of the main nutrients that bacteria need to multiply. By preventing protein production, clindamycin slows down bacterial growth that causes acne to develop.

Not only does clindamycin improve the appearance of inflamed acne, but it has also been shown to improve the skins inflammatory response to acne and infection. This means that the skin is able to prevent damage from spreading to nearby skin cells, recover from inflammation faster, and clear pores more efficiently.

Over time this results in fewer acne breakouts, as well as healthier and smoother-looking skin.

To avoid antibiotic resistance, clindamycin is often prescribed with other acne medications.

This includes products like benzoyl peroxide and topical retinoids. Well take a closer look at these ingredients later in this article.

Important Information About All Medicines

Does Clindamycin Work For Acne? Here is The Truth

This preparation is for external use only. If someone swallows some of it, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.

If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.

If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking or using.

This preparation is for you. Never give it to other people, even if their condition appears to be the same as yours.

Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.

If you have any questions about this preparation, ask your pharmacist for further advice.

Further reading and references

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What Is Clindamycin Used For

As an antibiotic, oral clindamycin can treat a variety of diseases, including :

  • Blood infections
  • Streptococcal pharyngitis
  • Malaria

Clindamycin lotion and gel are FDA-approved to treat acne , one of the most common skin conditions. Experts estimate that acne affects 4050 million people in the U.S. at any given time .

Clindamycin cream is typically used vaginally to treat bacterial vaginosis, a common cause of vaginal discharge.

Benefits Of Using Clindamycin For Acne

A 2007 study showed that clindamycin was more efficient than other topical antimicrobials like erythromycin and tetracycline in treating acne . Another study suggested that a nano gel emulsion made with 1% clindamycin was more effective in treating acne than other conventional gel formulations .

Research has also evaluated the effects of topical clindamycin hydrochloride and clindamycin phosphate in treating acne. They were compared with two non-prescription, anti-acne hydroalcoholic products . After eight weeks, the clindamycin formulations proved to be better for patients with moderate to severe acne. However, the study highlights the possibility of a placebo effect in this regard.

Topical clindamycin reduces the count of bacteria, like propionibacterium acnes, in sebaceous follicles by disrupting their growth. Pairing a topical antibiotic, like clindamycin, with benzoyl peroxide reduces resistance in the bacteria. These antimicrobials suppress the growth of propionibacterium acnes that is known to cause acne .

Clindamycin is thought to show better results when used in combination with other drugs. We have discussed them below.

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What Are The Adverse Effects Of Topical Clindamycin

There are several downsides to using clindamycin or other topical antibiotics!) for acne treatment. Prolonged use can make acne bacteria resistant to this antibiotic and, ultimately, make acne worse in the future. In fact, the risk of bacterial resistance from Clindamycin and other topical antibiotics has led to the American Academy of Dermatology recommending against using such topical antibiotics as a single solution for treating acne.

In addition to the risks of bacterial resistance and worsening of the acne condition long-term, clindamycin can be absorbed into the blood circulation and affect internal organs. Possible from using clindamycin include skin peeling, dryness, and irritation, while some also report diarrhea, vomiting, nausea, abdominal cramps/pain, and other unpleasant symptoms (according to the FDA

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To Use The Gel Follow These Steps:

Clindamycin versus benzoyl peroxide for acne| Dr Dray
  • Wash the affected area with warm water and gently pat dry with a clean towel.
  • Use you fingertips to spread a thin layer of gel evenly over the affected area. Avoid getting the gel in your eyes, nose, mouth, or other body openings. If you do get the gel in your eyes, wash with warm water.
  • Look in the mirror. If you see a white film on your skin, you have used too much medication.
  • Wash your hands.
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    How To Incorporate Clindamycin Into Your Skincare Routine

    Its normal to want to get the most out of your topical antibiotics right away, says Dr. Lilliana Ramirez Garcia, a board-certified dermatologist and the Director of Skincare Success at Nava MD. However, the key is following the correct application process and allowing your skin to build up a tolerance to these topicals.

    Below weve included some tips from Dr. Ramirez to help you incorporate clindamycin into your daily skincare routine.

    Give Your Treatments a Chance to Absorb

    Topical antibiotics are usually used in the initial stages of a skincare routine, which can affect their chances to fully absorb.

    To make sure you get the most out of your acne medications, we recommend waiting about five minutes before applying other products to get the most out of the treatment.

    Less Is More

    If you want to get the most out of prescription treatments, avoid saturating your skin with other products beforehand.

    Its a delicate balance, as you want to hydrate your skin before applying stronger products, but you also dont want to prevent the antibiotic from absorbing fully.

    This is why we recommend applying one layer of your moisturizer or toner to your skin before a topical antibiotic.

    Not only will this ensure that your skin stays hydrated, but it will also give any topical antibiotics the best possible chance of being absorbed.

    Keep Communicating

    Overcoming acne is a team effort between you and your dermatologist.

    A Step-by-Step Skincare Routine

    Step 1:
    Step 2:
    Step 3:

    Topical And Oral Clindamycin For Acne: Dosage Side Effects And More

    • Clindamycin is prescribed as an oral or topical antibiotic for bacterial infections
    • Topical clindamycin effectively treats mildsevere acne
    • Improvements can be seen within 26 weeks of starting treatment
    • Clindamycin is typically combined with other acne medications

    Acne vulgaris is a very common skin condition that develops when pores become clogged with oil, dead skin cells and debris. Bacteria plays a central role in acne development, making antibiotic therapy a staple in acne treatment. Clindamycin for acne is an antibiotic that is typically prescribed in combination with another medication for greater efficacy.

    If left untreated, mild symptoms can worsen and progress to more severe acne formation. Whether mild, moderate or severe, acne can cause long-lasting or permanent scarring.


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    Is Topical Clindamycin Safe To Use During Pregnancy Or While Breastfeeding

    • The frequency of congenital abnormalities was not increased when pregnant women used clindamycin during the second and third trimesters. Clindamycin has not been properly evaluated during the first trimester of pregnancy. It should only be used during the first trimester of pregnancy if it is clearly needed.
    • Oral clindamycin is excreted in breast milkand either should not be used bynursing mothers or nursing should be stopped. It is not known whether clindamycin given topically is excreted in breast milk.

    Does Clindamycin Work For Acne Here Is The Truth

    Clinsol Clindamycin Gel

    For most of the people, the popping acnes on your facial skin can be an irritating moment that ruins your perfect appearance. Particularly, the moderate to severe inflammatory acne will need a stronger treatment like with antibiotic therapy. When you look for acne medication, some of the doctors may recommend using clindamycin for acne treatment.

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    What Is Clindamycin And How Does It Treat Acne

    Clindamycin phosphate is an antibiotic that is typically used to fight a bacterial infection. You can find clindamycin phosphate in a topical form or as oral clindamycin medication. Antibiotic therapy is usually recommended for infections caused by bacteria, but antibiotic medicine can actually benefit inflammatory breakouts too!

    Our dermatologists may recommend an oral antibiotic like doxycycline as a treatment for severe acne. This helps to kickstart acne treatment, but they, unfortunately, cannot be used long-term. However, topical antibiotics can be used to safely keep acne under control long-term.

    Topical clindamycin for acne is typically used as a topical antibiotic to calm inflammation and reduce an acne causing bacterium called Cutibacterium acnes. It helps to calm inflammatory acne lesions and can also mildly improve non inflammatory lesions like blackheads.

    Important: How To Use This Information

    This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

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    Is Clindamycin Right For You As An Acne Treatment

    Clindamycin is an antibiotic that was first developed in 1966. It treats bacterial infections as well as acne, also called acne vulgaris. There are a myriad of different treatment options when it comes to acne and it can be difficult to sort which ones can be the most effective. Learn more as we discuss clindamycin for acne, how clindamycin works, the different forms of treatment, and whether it is the right form of acne treatment for you.

    The Benzoyl Peroxide In Duac Can Bleach Your Linens

    Clindamycin | Bacterial Targets, Mechanism of Action, Adverse Effects

    Wash your hands with soap right after applying your medication. Dont let the gel get on your clothing, pillowcases, towels, etc. or youll end up with orange stains.

    If you’re applying just before bed, you’ll probably want to use a white pillowcase. Other colors have a tendency to bleach out, even if the medication is fully dry before you go to bed. And pajamas may become stained, so wear pajamas that you don’t mind getting discolored.

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    Which Drugs Or Supplements Interact With Topical Clindamycin

    Clindamycin given orally may act as a neuromuscular blocker. This means it can increase the action of neuromuscular blocking drugs that block the contraction of muscles. Less clindamycin is absorbed into the blood stream when given topically so the likelihood of this drug interaction is less likely.

    Does Clindamycin Make Acne Worse Before It Gets Better

    Clindamycin is an antibiotic, and it is used to treat acne. Although it has several other uses such as treating malaria. But it is more popular for treating acne this is especially for inflammatory and infected acne breakouts. Clindamycin is quite popular because several types of research have supported its use for acne and it does not worsen acne breakouts.

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    Types Of Topical Clindamycin

    Topical clindamycin is available in a variety of forms. This includes:

    • A foam or gel moisturizer
    • A clindamycin-coated patch or pad
    • A lotion

    Your dermatologist will advise you on how regularly to use clindamycin, as well as what form is best for your skin.

    You may have heard of clindamycins most common brand names. These include ClindaMax, Clindagel, Evoclin and Clinda-Derm, to name just a few. Today, most clindamycin used is generic, meaning it costs much less than name-brand versions.

    D Other Topical/new Agents

    Almost one year on Curology (my blend has Azelaic Acid, Clindamycin ...

    Combination therapy: Benzoyl peroxide has the advantage to prevent and eliminate the development of P. acne resistance. Therefore it is being more preferred as combination therapy. Its efficacy and tolerability are enhanced when combined with topical erythromycin or clindamycin, confirmed on various trials. Benzoyl peroxide can be combined with tretinoin and found to be superior to monotherapy. Both the molecules should not be applied simultaneously as benzoyl peroxide may oxidize tretinoin. A combination of topical retinoid and topical antimicrobial is more effective in reducing both inflammatory and noninflammatory acne lesions than either agent used alone. Topical clindamycin and benzoyl peroxide applied once daily and fixed clindamycin phosphate 1.2% and tretinoin 0.025% in aqueous-based gel formulation used once daily are both found to be effective treatment for acne. Addition of zinc acetate to clindamycin and erythromycin gel showed equivalent efficacy but probably reduces the development of microbial resistance.

    Salicylic acid: It has been used for many years in acne as a comedolytic agent, but is less potent than topical retinoid.

    Azelaic acid: It is available as 1020% topical cream which has been shown to be effective in inflammatory and comedonal acne.

    Lactic acid/Lactate lotion: It is found to be helpful in preventing and reduction of acne lesion counts.

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    Benefits Of Clindamycin For Acne

    • Reduces acne-causing bacteria: One of the biggest benefits of clindamycin for acne is that it decreases acne-causing bacteria. “As an antibiotic, it helps to reduce acne-causing bacteria and can be particularly helpful for inflammatory acne,” explains Garshick.
    • Pregnancy-safe option for acne: If you’re pregnant, your options for safe, acne treatments are limited, since it’s not safe to use treatments like retinol or salicylic acid. ” is considered pregnancy-safe so it is a good option for those who are pregnant and looking to treat their acne,” says Garshick.
    • Minimal side effects: According to Karam, clindamycin has minimal side effects topically. “Most of it would be related to the ingredients of alcohol, which can create some burning sensation to the skin and dryness.”
    • “You can decrease the potential for infection and inflammation of the pores, which leads to acne from occurring,” adds Karam.

    What Else Should I Know About Topical Clindamycin

    What preparations of topical clindamycin are available?
    • Gel, foam, lotion, solution, swab: 1%
    How should I keep topical clindamycin stored?
    • Clindamycin topical preparations should be stored at room temperature, 20 C to 25 C .
    How does topical clindamycin work?
    • Clindamycin reduces growth of bacteria by interfering with their ability to make proteins.
    When was topical clindamycin approved by the FDA?
    • The FDA approved clindamycin for topical use in July, 1980.

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    Benefits Of Clindamycin In Acne How To Use It & Customer Reviews

    Acne is a skin disease which affects millions of people around the world and can range from being non-severe to acutely severe developing in forms of nodules and cysts in acute cases.

    It has been noted by the Food and Drug Administration , that in the past year, 17 million prescriptions were written by physicians for acne treating products and clindamycin and retinoid accounted for 8 million out of the total 17 million prescriptions.

    Clindamycin, as such, comes forth as an important treatment for acne.

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